Prostate Study

http://medcraveonline.com/MOJCR/MOJCR-02-00022.pdf

This research has been presented at the International Pain Conference in Chicago, June 7-10, 2015 Chicago, IL.

http://painmedicine.conferenceseries.com/organizing-committee.php

Prof. George Grant has completed a clinical study for 24 subjects using all natural herbal formula over 6 months to reduce the symptoms of enlarged prostate and elevated PSA.

Preventing Prostate Cancer Diet and Lifestyle Modification:

Given the reality that PSA screening for early detection for prostate cancer is a misguided adventure which leads to over diagnosis and does more harm than good, perhaps another approach to prevention is warranted. A nutritional program for prostate cancer prevention with Vitamins C, B6, E, zinc, selenium, Saw palmetto, Pygeum africanum, stinging nettle, pumpkin seed, Echinacea purpurea, garlic, ginkgo biloba, Amino acids L glycine, L alanine, L glutamic acid and Modified Mediterranean Diet.

More on Prostate Health: http://www.your101ways.com

Evaluating the efficacy of IPM [Ionic Polymer Matrix] made with Hyaluronic Acid [HA] with natural herbal ingredients in the reduction of prostatis [Prostate Inflammation] for 12 male subjects over 3 months.

Dr. George Grant, Ph.D., I.M.D., D.H.S., M.Sc., M.Ed., C.B.S., C.Chem, R.M.

Dr. George Grant discusses the results of a case study to evaluate the efficacy of IPM transdermal cream made with hyaluronic acid along with natural herbal ingredients in the reduction of prostate inflammation over 3 months for 12 male subjects ranging from mid-forties to mid-seventies.

Abstract:

After using the natural IPM transdermal cream for 3 months by 12 volunteer subjects, the improvement in the reduction of frequent urination during the day and at night was over 12.5% using both biofeedback and PSA testing.
Using natural herbal formula to reduce BPH instead of using prescription medications with unpredictable and sometimes serious side effect is an innovative approach with promising successful management of BPH among men.

Patent Assignment:

United States Patent and Trademark Office
Your assignment has been received by the USPTO.
The coversheet of the assignment is displayed below:

SUBMISSION TYPE: NEW ASSIGNMENT
NATURE OF CONVEYANCE: ASSIGNMENT
CONVEYING PARTY DATA
Name Execution Date
Dr. George Grant 07/08/2013
RECEIVING PARTY DATA
Name: Glyco Bio Sciences, Inc.
Street Address: 10 Mountainview Road South
Internal Address: Suite 207, City: Georgetown, CANADA, L7G 4J9
PROPERTY NUMBERS Total: 1
Property Type Number
Application Number: 61810380
USPTO. EPAS. Receipt Page 1 of 2
http://epas.uspto.gov/com/receipt.jsp?iname=VJHNRT1QQB8U-8162 07/11/2013CORRESPONDENCE DATA
Fax Number: 2484407300
Phone: 2484305772
Email: patdocketing@bluefilamentlaw.com
Correspondent Name: Avery Goldstein
Address Line 1: 450 north Old Woodward
Address Line 2: First floor
Address Line 4: Birmingham, MICHIGAN 48009
ATTORNEY DOCKET
NUMBER: GLYC-105PRV
NAME OF SUBMITTER: Avery Goldstein
Signature: /Avery Goldstein/
Date: 07/11/201

Conflict of interest disclosure: The author is not employed nor compensated by Glyco Bio Sciences the manufacture of the IPM matrix. The company provided the transdermal matrix at no charge to conduct the case study for 12 subjects at our clinic in Toronto, ON Canada. The author has no financial interest in the company.

Subject Selection Criteria: 12 healthy male subjects with mild to moderate enlarged prostate were selected to participate in this case study and signed an informed consent. Subjects with medical, psychiatric conditions and those with heavy medications were excluded from the study.
Subjects were tested using bio feedback device before and after using the IPM transdermal matrix and a fasting 12 hours CBC blood test to measure PSA levels was obtained from each subject before and after 3 months at the completion of the case study.

Objectives of the Study:

The main purpose of this research is to evaluate the efficacy of the IPM/HA Matrix with natural herbal ingredients to reduce the symptoms of enlarged prostate [BPH] in 12 subjects over 3 months.

Introduction, Protocol and Description of the Research:

The following natural herbal ingredients were encapsulated in HA gel and applied transdermally once every night before bed time:

Turmeric/Curcumin 100 mg: Curcumin, an active ingredient of the Indian spice Turmeric, has been shown to stop the formation of metastases in prostate cancer patients, researchers from LMU University in Munich, Germany, reported in the journal Carcinogenesis today.

Beta Sitosterol 100mg: Beta Sitosterol is a phytosterol, which means it is a phytochemical that occurs naturally in many plants.

prostatestudyrevised

Fat Content and Cardiovascular Disease
Dairy productsincluding cheese, ice cream, milk, butter, and yogurtcontribute significant amounts of cholesterol and saturated fat to the diet.15 Diets high in fat and especially in saturated fat can increase the risk of heart disease and can cause other serious health problems.

A low-fat, plant-based diet that eliminates dairy products, in combination with exercise, smoking cessation, and stress management, can not only prevent heart disease, but may also reverse it.

The danger of dairy product consumption as it relates to prostate and breast cancers is most likely related to increases in insulin-like growth factor (IGF-1), which is found in cows milk. Consumption of milk and dairy products on a regular basis has been shown to increase circulating levels of IGF-1. Perhaps the most convincing association between IGF-1 levels and cancer risk is seen in studies of prostate cancer. Case-control studies in diverse populations have shown a strong and consistent association between serum IGF-1 concentrations and prostate cancer risk. One study showed that men with the highest levels of IGF-1 had more than four times the risk of prostate cancer, compared with those who had the lowest levels.26 In the Physicians Health Study, tracking 21,660 participants for 28 years, researchers found an increased risk of prostate cancer for those who consumed ≥2.5 servings of dairy products per day as compared with those who consumed 0.5 servings a day. This study, which is supported by other findings, also shows that prostate cancer risk was elevated with increased consumption of low-fat milk, suggesting that too much dairy calcium, and not just the fat associated with dairy products, could be a potential threat to prostate health.

In addition to increased levels of IGF-1, estrogen metabolites are considered risk factors for cancers of the reproductive system, including cancers of the breasts, ovaries, and prostate. These metabolites can affect cellular proliferation such that cells grow rapidly and aberrantly, which can lead to cancer growth. Consumption of milk and dairy products contributes to the majority (60-70 percent) of estrogen intake in the human diet.

In a large study including 1,893 women from the Life After Cancer Epidemiology Study who had been diagnosed with early-stage invasive breast cancer, higher amounts of high-fat dairy product consumption were associated with higher mortality rates. As little as 0.5 servings a day increased risk significantly. This is probably due to the fact that estrogenic hormones reside primarily in fat, making the concern most pronounced for consumption of high-fat dairy products.

The consumption of dairy products may also contribute to development of ovarian cancer. The relation between dairy products and ovarian cancer may be caused by the breakdown of the milk sugar lactose into galactose, a sugar which may be toxic to ovarian cells. In a study conducted in Sweden, consumption of lactose and dairy products was positively linked to ovarian cancer. A similar study, the Iowa Women’s Health Study, found that women who consumed more than one glass of milk per day had a 73 percent greater chance of developing ovarian cancer than women who drank less than one glass per day.

Prostate cancer is one of the most common cancers in men. According to the latest statistics, about 181,000 men get diagnosed with prostate cancer every year in the U.S.

However, while common, it has a survival rate of about 86 percent. Of those diagnosed, about 26,000 die from the disease each year.¹

Unfortunately, conventional diagnostics and treatment options for prostate cancer leave much to be desired. Conventional diagnosis includes PSA testing and biopsy, which are prone to false positives and carry risks of side effects.

Treatment typically involves drugs, surgery and/or radiation, all of which are risky. There ARE safer, less invasive ways to diagnose and treat prostate cancer, however, so men would be wise to investigate their options.

Last year, I interviewed award-winning filmmaker and prostate cancer survivor Peter Starr on this topic, which is also covered in his latest documentary, “Surviving Prostate Cancer Without Surgery, Drugs or Radiation.”²

A number of safe and all-natural strategies have been shown effective against prostate cancer, including nutritional ketosis, exercise and supplements. Most recently, researchers discovered a bioactive compound in the neem plant (Azadirachta indica) appears to have potent ability to quell prostate cancer.

Neem Has a Long History of Medicinal Use

Neem has been used in Ayurvedic medicine for thousands of years, and the ancient Vedas refer to neem as a tree “capable of curing every illness.” It has well-established benefits for your skin, and is commonly used in personal care products.³

It also is used to ease gastrointestinal problems and strengthen immune function, and as both a spermicide and an insect repellent. As noted in the Biojournal of Science and Technology (BJST):⁴

“[Neem’s] leaves, barks, fruits, seeds and roots contain compounds with proven anti-inflammatory, anti-pyretic, anti-histamine, anti-fungal, antibacterial, anti-ulcer, analgesic, anti-arrhythmic, anti-tubercular, anti-malarial, diuretic, spermicide, anti-arthritic, anti-protozoal, insect repellant, anti-feedant, anti-hormonal properties and anti-cancerous uses.

From various research articles it can be presumed that [neem] has chemopreventive and chemotherapeutic potential against cancer models [including] acting against the breast cancer cells, against gastrointestinal tract and associated cancers [and] ovary cancer cells.”

Neem May Be a Potent Ally Against Prostate Cancer

Now, animal research suggests nimbolide a bioactive terpenoid compound found in neem may shrink prostate tumors by as much as 70 percent, and suppress metastasis by about 50 percent when taken orally for three months.^5,6,7,8 No noticeable side effects were observed.

According to lead researcher Gautam Sethi, Ph.D., associate professor of pharmacology at the Yong Loo Lin School of Medicine at the National University of Singapore:⁹

“Although the diverse anti-cancer effects of nimbolide have been reported in different cancer types, its potential effects on prostate cancer initiation and progression have not been demonstrated in scientific studies.

In this research, we have demonstrated that nimbolide can inhibit tumor cell viability a cellular process that directly affects the ability of a cell to proliferate, grow, divide or repair damaged cell components and induce programmed cell death in prostate cancer cells

[A] direct target of nimbolide in prostate cancer is glutathione reductase, an enzyme which is responsible for maintaining the antioxidant system that regulates the STAT3 gene in the body.

The activation of the STAT3 gene has been reported to contribute to prostate tumor growth and metastasis. We have found that nimbolide can substantially inhibit STAT3 activation and thereby abrogating the growth and metastasis of prostate tumor.”

Other Research Supporting Neem as an Anti-Cancer Aid

While exceptionally promising in rodents, nimbolide has not yet been tested in humans, so further research will be required. The team intends to continue investigating the compound to evaluate its efficacy in combination with commonly used prostate cancer drugs as well.

That said, consuming neem either in supplement or tea form will automatically provide nimbolide.

Even though the whole herb will provide only a small amount of nimbolide (compared to the straight compound given to the animals in this study), previous research has indeed found neem extract to be useful against prostate cancer. In 2006, researchers reported that:¹⁰

“[A]n ethanolic extract of neem has been shown to cause cell death of prostate cancer cells by inducing apoptosis as evidenced by a dose-dependent increase in DNA fragmentation and a decrease in cell viability So the neem extract could be potentially effective against prostate cancer “

Lifestyle and Prostate Cancer

Treating and preventing prostate cancer (and other cancers) requires more than taking a supplement. Your diet is a vital part of the healing equation and exercise is another important metabolic optimizer.

Previous research suggests losing weight can reduce your risk of prostate, breast and colon cancer by as much as 20 percent, and this effect is thought to be due to reductions in these proteins and other inflammatory compounds stored in fat cells.¹¹

According to a 2011 study published in PLoS One,¹² aggressive prostate cancer was associated with obesity.

Another cohort study published in Cancer Epidemiology, Biomarkers & Prevention¹³in 2013 found that men who were overweight or obese increased their risk of prostate cancer by 57 percent.

Here, the association between obesity and prostate cancer held for all cases low-grade and high-grade, early stage and late, nonaggressive and aggressive prostate cancer.

When it comes to exercise, research suggests maintaining a high level of cardiorespiratory fitness (CRF) in middle age helps cut men’s chances of dying from prostate cancer by nearly one-third (32 percent).^14,15

Exercise reduction of cancer is most likely related to improving insulin receptor sensitivity and PGC 1-alpha that increases mitochondrial biogenesis.

Optimizing your vitamin D level, which is ideally done through sensible sun exposure, is another key ingredient for cancer prevention. Vitamin D deficiency has been linked to several common cancers, including cancers of the breast, colon and prostate.

Researchers at Northwestern University Feinberg School of Medicine recently discovered that men diagnosed with aggressive prostate cancer tend to have vitamin D levels below 23 nanograms per milliliter (ng/ml). According to this study, vitamin D may actually be used as a biomarker to predict cancer:

“[B]ecause vitamin D is a biomarker for bone health and aggressiveness of other diseases, all men should check their levels, [lead investigator Dr. Adam] Murphy said.’All men should be replenishing their vitamin D to normal levels,’ Murphy said. ‘It’s smart preventive health care.'”

You can also improve your benefit from vitamin D by increasing your healthy levels through sensible sun exposure and not by swallowing it.

Other Important Anti-Cancer Nutrients

In addition to vitamin D, vitamin K2 appears to be a noteworthy player in prostate cancer.

German doctors evaluating the effect of vitamins K1 and K2 on the development and treatment of prostate cancer found that those who consumed the greatest amount of K2 had a 63 percent reduced incidence of advanced prostate cancer.^16,17

Vitamin K1 intake did not offer any prostate benefits. Other nutrients and foods shown to influence your prostate cancer risk include (but are not limited to) the following:

Supplements That Support Prostate Health

Besides neem extract, other nutritional supplements that promote prostate health may be helpful in the prevention and/or treatment of prostate cancer, such as:

Toxins May Increase Your Prostate Cancer Risk

Avoiding toxins is also important. As with breast cancer, many of the chemicals that are ubiquitous in our homes and environment have been shown to increase your risk of cancer. Some of the most common culprits are those that disrupt your endocrine function.

Based on a review of more than 1,300 studies, an Endocrine Society task force recently issued a new scientific statement^28,29 on endocrine-disrupting chemicals, noting that everyone needs to take proactive steps to avoid them.

Similarly, a report³⁰ co-produced by the World Health Organization (WHO) and the United Nations Environment Program (UNEP), issued in February 2014, suggests an outright ban on endocrine disrupting chemicals may be needed to protect the health of future generations.

Touted as the most comprehensive report on endocrine disrupting chemicals to date, it highlights a wide variety of health problems associated with exposure, including prostate cancer. Some of the most ubiquitous endocrine disrupters to watch out for include:

Should You Get Screened for Prostate Cancer?

According to a report by the Institute of Medicine, approximately 30 percent of all medical procedures, tests and medications may be unnecessary.³⁵ The American Academy of Family Physicians’ (AAFP) “Choosing Wisely” campaign has also identified more than a dozen procedures that appear to have little value, and in many cases do more harm than good.³⁶ Included in this list is routine screening for prostate cancer using a prostate-specific antigen (PSA) test.

The PSA test tends to result in over-diagnosis of prostate tumors, many of which are benign and do not actually require treatment. The U.S. spends $10 billion per year treating prostate cancer, but studies suggest the 30 million men who get screened annually for prostate cancer are actually put at risk due to the ridiculously high numbers of false positives.

According to the Prostate Cancer Foundation, 30 to 40 percent of men treated for prostate cancer actually have harmless tumors that would never have caused a problem.³⁷ As noted by Dr. Jessica Herzstein, a preventive-medicine consultant and member of the U.S. Preventive Services Task Force, “You’re going to die with them, not of them.”

Estimates suggest 15 prostates must be removed in order to prevent just ONE prostate cancer death, and these surgical procedures carry serious side effects including impotence and incontinence.

More than half of older men have pathologic evidence of prostate cancer, so PSA screening makes little sense. The PSA is an indicator of inflammation, and inflammation can be an indicator of health problems besides prostatitis, benign prostatic hyperplasia or cancer. It’s certainly not a definitive test, and should not be the sole basis for the decision to do a biopsy, as the biopsy itself can cause significant damage.

One alternative is to get an annual digital rectal exam. Your doctor can feel your prostate to find out whether it’s hard, or whether there are noticeable nodules. Then, rather than getting a biopsy done right away, consider getting a 3D-color Doppler ultrasound done first. For more information, please see my previous article, “How to Survive Prostate Cancer Without Surgery, Drugs or Radiation.”

To Prevent Cancer, Remember the Basics

Remember, your lifestyle can be more or less predictive of your cancer risk, so always start with the basics: Make sure you’re eating a nutrient-dense, non-toxic diet, which basically means ditching processed foods and focusing your diet around whole, fresh foods, ideally organically grown to avoid toxic pesticides that can increase your cancer risk.

Avoid animal products from concentrated animal feeding operations (CAFOs), as these animals are routinely raised with hormones, antibiotics and glyphosate-contaminated genetically engineered (GE) grains. Processed foods in general are anathema to good health, but particularly when you’re trying to prevent or heal cancer.

If a toxicology screen reveals high amounts of toxins in your body, a detoxification program would be in order. My absolute favorite form of detox is a full spectrum infrared sauna that has near-infrared frequencies and low EMF. Most infrared saunas have only far-infrared and are high in EMF. I believe selecting a sauna that keeps your head out of the heat is also important and I am working on developing one that meets this spec early next year.

You may also want to do a saliva panel to check your hormone levels. Low testosterone and/or excessive estrogen may be factors that need to be corrected. For low testosterone, you could start out with herbal supplements, high intensity exercise and/or intermittent fasting rather than jumping right into testosterone replacement therapy.

Also remember to check your vitamin D. For optimal health and cancer prevention, make sure you maintain a clinically relevant level of 40 to 60 ng/ml year-round. If you already have cancer, you may want to consider an even higher level.

You Can Prevent, and Beat, Prostate Cancer

Checking for insulin resistance goes along with your dietary intervention. If you’re insulin resistant, you need to be particularly careful about cutting down on sugar, ideally limiting your total fructose consumption from all sources to less than 15 grams per day. Thankfully, nutritional ketosis is one of the best ways to improve your insulin receptor sensitivity.

If you are overweight, you can use fasting as a very powerful therapeutic tool and the best resource for that is Dr. Jason Fung’s book “The Complete Guide to Fasting.” I would strongly encourage you to listen to my recent interview with Fung.

Another powerful tool to maintain nutritional ketosis is intermittent fasting. Nutritional ketosis is not something you maintain for your entire life, but is part of a feast and famine cycling that allows your body to repair and regenerate while maintaining its ability to burn fat.

Once you’ve cleaned up your diet, adding certain herbal supplements such as saw palmetto (with or without astaxanthin) and Ashwagandha may help support your prostate health.

These are just some suggestions that can minimize your risk of prostate cancer and help treat it should you be diagnosed. There are many others. For example, increasing selenium and magnesium while decreasing calcium may reduce your prostate cancer risk, and simple strategies such as prostate massage can be a helpful adjunct to prostate cancer treatment.

The main take-home message is that you have options when it comes to prevention, diagnostics and treatment. Also remember that, while any cancer diagnosis is distressing, when it comes to prostate cancer, you likely do have time to pursue alternative routes of treatment. Rarely is it necessary to jump right into drugs, surgery or radiation. So try not to let fear rule your decision-making process.

How successful ? EBC46, injected directly into the tumor, can kill it in just 48 hours.

For more information and to be considered for a trial, click here.

Blushwood berries are the fruit of the blushwood tree, which is known to grow in only one region of the world: the rainforests of Far North Queensland, Australia.

These tropical trees are not found anywhere else on the globe, but grow in abundance near Australias northeastern tip.

These particular trees need very niche conditions to thriveconditions which can only be found in specific portions of Far North Queensland, Australia.

Considering their usefulness as proven by the latest cancer research published in PLOS One, some are wondering if they could be grown in a greenhouse environment, so that people all over the world could benefit from their cancer-killing properties.

Its been twenty-one years since the first study reported a possible link between elevated serum selenium and prostate cancer risk reduction. In the years since, research has continued to explore this minerals role in cancer risk reduction. A literature review in the journal Medicine released this week continues the steady stream of research supporting this viewpoint.
Seventeen of 1352 studies (up to Sept. 2016) were identified as suitable from PubMed, Embase, Medline, and the Cochrane Library. The final review included 6136 prostate cancer cases and >34,901 controls or participants.

Prostate cancer is the second most common form of cancer in men, and the sixth leading cause of cancer deaths in developed countries. Characterized by difficulty and pain in urination, increased frequency of urination and blood in urine this condition also results in embarrassments to affected individuals as urine leaks out while coughing or laughing. Although some of these symptoms might be because of an enlarged prostate, it is advised to screen for prostate cancer if one is over 50 years of age. It is estimated that by 2030, 1.7 million new cases and 499,000 fatalities might be because of this deadly disease (World journal of Surgical Oncology, 2012). This year alone, the American Cancer Society has estimated 161,360 new cases of prostate cancer and 26,730 deaths in the United States (www.cancer.org/cancer/prostate-cancer).

Prostate gland, a part of the male reproductive system, is a tiny walnut sized gland that performs the task of regulating the passage of semen and urine. The fluid secreted by the prostate gland makes up one third of the semen, protecting and nourishing the sperms. Urine and semen are released from the body through a tube like structure urethra that passes through the prostate gland, which controls this process with the help of numerous muscle fibers. Cancerous growth in such a vital organ can severely impact different physiological processes, besides causing threat to ones life.

Prostate cancer has an average diagnosis age of 66 years, with 6 out of 10 cases reported in men above the age of 65 years. It is generally treated through surgery, hormone therapy, radiation therapy, and chemotherapy. Although these treatments are successful, the toxic side effects of these procedures are of great concern. Alternative systems of medicines, like ayurveda, promise zero side effects with desired benefits, forcing many to go green. It is not surprising that some herbal drugs prepared using plant extracts are already being used to treat cancer. In fact, Taxol, a famous chemotherapy agent used for different types of cancers was extracted from the bark of Taxus brevifolia. Now, a research group led by Dr. M.B. Hiremath, Associate Professor at Karnataka University, Dharwad, has recently reported the anti-cancer potential of two medicinal plants Leea indica and Allophylus cobbe, against prostate cancer.

Leea indica, or bandicoot berry (kukur jihwa in Hindi) is a large, evergreen shrub, native to tropical India, Bangladesh, China, Bhutan, and Malaysia. It is used in traditional medicine to relieve headaches, skin problems, body aches and for its antidiabetic, antidiarrheal and antidysenteric properties. Allophylus cobbe, also called Indian allophylus, is a small shrub and commonly seen in the Western Ghats of India and used for treating bone fractures, inflammations, ulcers and wounds as a natural antiseptic. While these plant extracts have already shown cytotoxic properties on colon and breast cancer cells, this study is the first to examine the effects on prostate cancer.

The researchers of the study tested the extracts prepared by treating the leaves of the two plants in water, methanol and ethanol on cancerous cells of the prostate and found them to be very effective. During the study, we witnessed gradual deterioration of prostate cancer cells by undergoing morphological changes in shape and size and eventually reaching apoptosis (programmed cell death) after 72 hours of exposure to these natural extracts, shares Dr. Hiremath, talking about the effectiveness of these plant-based extracts. The results of their studies have been recently reported in two journals Cytotechnology and Integrative Medicine Research.

The researchers have reported the presence of a range of secondary plant metabolites like phenols, alkaloids, flavonoids and saponins in the leaves of the two plants. These metabolites have proven to be strong antioxidants that destroy harmful free radicals present in our body. Both the plant showed high phenolic content in our study. Interestingly, the antioxidant capacity of the plant extracts studied is also closely equivalent to the standard antioxidant agents like ascorbic acid, explains Dr. Hiremath about their interesting findings.

The researchers hope to soon test the efficiency of these extracts in humans through clinical trails. Our findings have shown positive results at in vitro level (outside human body). These outputs have given a positive stand point to take on further studies using living systems to establish the potential of these extracts to be used as therapeutic agent to fight prostate cancer, signs off Dr. Hiremath, detailing the future of the study.
Source: Yahoo! News Australia

New research from The University of Texas at Austin identifies several natural compounds found in food, including turmeric, apple peels and red grapes, as key ingredients that could thwart the growth of prostate cancer, the most common cancer afflicting U.S. men and a key area of focus during Mens Health Month, which public health advocates celebrate in June, reports the University of Texas in Austin. Published online this week in Precision Oncology, the new paper uses a novel analytical approach to screen numerous plant-based chemicals instead of testing a single agent as many studies do, discovering specific combinations that shrink prostate cancer tumors.
Ursolic acid from apple peels
Curcumin from turmeric
Resveratrol from red grapes
The new research paper also demonstrates how the plant-based chemicals work together. Combining ursolic acid with either curcumin or resveratrol prevents cancer cells from gobbling something that they need to grow, glutamine. This is a neat solution: blocking the uptake of a nutrient needed by prostate cancer cells with nutrients that are commonly in the human diet.

Last year a government task force reversed five years of advice on whether men should have a prostate specific antigen (PAS) test to screen for prostate cancer. The U.S. Preventive Services Task Force reversed itself, it said, and once again began advising men to be screened because new evidence indicated that routine PSA blood tests can slightly reduce some mens chances of dying from prostate cancer and that drastic treatment can sometimes be avoided with close monitoring when cancer is detected.

But new research published this week in one of the worlds most prestigious medical journals, the Journal of the American Medical Association (JAMA), debunks that argument. If orthodox medicine was actively working to muddle the issue of prostate health and the PAS test, it couldnt do a better job of throwing men into confusion on the subject than this.

The study by a team of researchers at the University of Bristol and University of Oxford found that PSA screening could only identify low-grade prostate diseases and failed to detect some aggressive and lethal prostate cancers.

As Medical News writes, researchers conducted the largest-ever prostate cancer trial over a decade, studying 400,000 men between ages 50 and 69. The trial compared 189,386 men who had a single PSA screening with 219,439 men who were not invited for screening.

After a decade of follow up, the total number of cases of prostate cancers reported in both the screening group and the control group were 8,054 (4.3 percent) and 7,853 (3.6 percent), respectively; however, the percentage men dying from prostate cancer in both the groups was 0.29 percent.

In other words, there was no difference in prostate cancer deaths between the tested and the untested group.

This has long been the consensus of those of us in the alternative medical community, and Ive been writing about it for years. Research has long placed substantial doubts about the validity and reliability of the PSA test. Even so, conventional doctors continue to use the test and rely on it to determine male prostate health.

Here is the point: The literature says a low PSA number of about four indicates a normal or healthy prostate, whereas higher numbers put prostate health in doubt and even suggests malignancy. A higher number, of course, calls for biopsy and may lead to prostate surgery.

Yet some men may have prostate malignancy with very low PSA numbers or no malignancy with very high PSA numbers.

This makes the whole test doubtful. I personally would not rely on the PSA test and would certainly refuse prostate surgery based on it or even biopsy at my age, 85.

Many men have been ruined because of prostate surgery. At the very least, all considerations of prostate surgery should be preceded by a detailed understanding of the pros and cons of relying on the PSA test.

Researchers participating in this latest trial agree.

The results highlight the multitude of issues the PSA test raises causing unnecessary anxiety and treatment by diagnosing prostate cancer in men who would never have been affected by it and failing to detect dangerous prostate cancers. Cancer Research UK is funding work that will allow us to follow the men for at least a further five years to see whether there is any longer-term benefit on reducing prostate cancer deaths, said Professor Richard Martin, lead author of the study.

Our large study has shed light on a highly debated issue. We found that offering a single PSA test to men with no symptoms of prostate cancer does not save lives after an average follow-up of 10 years, Martin said.

Integrative medicine specialists have told me to a man that a high PSA reading does not indicate cancer. Instead it indicates that something is going on to inflame the prostate. That something could indeed be cancer, but it is much more likely that a high reading is due to a recent infection or a completely benign enlargement of the prostate gland.

The literature claims that many or most men age 50 and older have dormant prostate cancer and that most never become active.

There are quite a few herbs and other plant extracts that help with prostate health, including pumpkin seeds, saw palmetto and stinging nettle. But the two most important things for your prostate are exercise and nutrition.

To prevent prostate enlargement and cancer, you should strive to be as active as possible. At least walk as much as possible. Walking often has the same health benefits as running, without the inflammatory side effects. A study last year performed in Sweden that suggested more intense exercise can cut your risk of prostate cancer in half. Further, the researchers discovered that exercising with vigor for 60 minutes inhibited the growth of existing cancer cells by over 30 percent.

I believe that prostate health is also based on diet plus whether one is a smoker or heavy drinker. Its obvious that unhealthy lifestyles will lead to unhealthy outcomes.

Zinc is your most basic prostate food, along with another essential mineral, selenium. They work together to maintain cellular health and are must-have for mens health because they reduce aromatase, and enzyme you want to reduce because it converts testosterone into estrogen, putting you on the path to reproductive cancers.

Spinach, beans, red meat, pumpkin seeds and oysters all have plenty of zinc in them, and for selenium, tuna and Brazil nuts should give you all you need.

Here is the thing about zinc that is not well known but important. It can interfere with the absorption of other minerals. That is why you want to take zinc separately, preferably before you go to bed so that you have a whole night of sleep to absorb it, and before taking any other supplements during the day.

If you suffer from prostate problems, then you may have heard that they’re caused by DHT (di-hydro-testosterone). But did you know that your toilet paper could also be to blame? It’s true!

Here’s why

Scientists have found that many brands of toilet paper contain a toxic chemical called BPA.You may know BPA as a chemical found in plastics. It’s in water bottles, food containers, and even baby toys. And guess what? It’s also in toilet paper, thanks to contamination during the recycling process!

You see, many toilet papers are made from recycled paper. And some of the papers being recycled come from magazines, credit card receipts, and other papers that are coated with plastic. As a result, BPA makes its way into the toilet paper. In fact, a government study found that 81% of all paper products contain BPA in them!1

Research shows that BPA is easily absorbed into the body through contact with the skin.2 And with toilet paper, it’s even worse than regular paper. Why? Because you’re wiping with toilet paper onto your anus. Not only is your anus right next to your prostate, but it contains lots of blood vessels.

So when you’re wiping with BPA-laden toilet paper, the toxin goes right into your bloodstream. It’s as if you were giving yourself a BPA suppository!

When BPA goes into your bloodstream, it can wreak havoc on your prostate health and sexual function. This has been demonstrated in several studies.

One study found that patients with unhealthy prostates had much higher BPA than people with healthy prostates. Another study found that BPA stimulates prostate cell growth, even in tiny amounts.3 And yet another study found that BPA can reduce daily sperm production by a whopping 20%!

Why is BPA so damaging to your prostate and sexual health? Well, it has to do with its ability to mimic estrogen. As you may know, BPA is chemically similar to estrogen. It can actually mimic estrogen and cause your body’s levels to shoot up. This can lead to estrogen building up in your prostate.

When estrogen builds up in your prostate, you have an imbalance of estrogen and testosterone. To compensate, your body converts testosterone into dihydrotestosterone (DHT). You see, DHT is 10 times stronger than regular testosterone. So your body converts as much testosterone as it can into DHT, in order to undo the adverse effects of rising estrogen.

But there’s a downside to DHT. DHT stimulates prostate cell growth, and causes your prostate to swell up until you have trouble peeing.

As your prostate gets bigger and bigger, you begin to lose urinary control. What happens next? Well, you may need to get up several times at night to rush to the bathroom. You may need to look for the men’s room everywhere you go. When you try to pee, you may dribble in stops and starts. And you may feel like you never fully empty your bladder.

Leads to Baldness
In addition to prostate problems, DHT can also cause hair loss and male pattern baldness. It does so by causing hair follicles on your head to shrink until they stop growing hair.

And that’s not all. As your body keeps turning testosterone into DHT to counter the rising estrogen, your testosterone levels plummet. Eventually, your body can no longer keep up. And you end up with too much estrogen and too little testosterone.

Too much estrogen and too little testosterone can result in low sex drive and weaker erections. It can ruin your sex life! Not only that, it can also lead to softer

Everyday Objects That Can Turn You Into A “Girly Man”
Don’t let this happen to you!
Scientists have found toxins that act like estrogen in many of the things we come into contact with each day. Things like: Dollar bills/napkins/Paper towels/Food contact papers/flyers/Magazines/Store receipts etc.
Studies show the toxins in these items can easily get absorbed into your body through the skin. Or the toxins can be transferred to your hands, and then to the food you hold and eat.

Once in your body, these toxins can throw your body out of whack. Like estrogen, they can cause your testosterone levels to plummet. They can make your muscles softer, and your arms and legs flabby. They can even cause you to grow “man boobs” and make you look more feminine.

The good news is, you don’t have to let this happen to you. Keep reading to discover a simple way to protect yourself from estrogen like toxins in the environment.

muscles and flabby arms and legs. It can even cause you to grow “man boobs” and make you look more feminine.

In addition, research shows too much estrogen can also lead to other health problems. These include uncontrolled weight gain, mood swings, dangerous blood clots, heart problems, and more.

By now, you can see why BPA is so hazardous to your prostate and overall health. And BPA is not just in toilet paper. It’s also found in many everyday things, including paper money store receipts credit card receipts magazines airline tickets food cartons napkins and even dental fillings.4

And it gets worse. In addition to BPA, there are many other estrogen-like chemicals in the environment. These include PCBs in soil and water dioxin in polluted air phthalates in shampoos and soaps pesticide residues in our food plus many more. It’s virtually impossible to avoid exposure to these environmental estrogens.

Luckily, there’s a simple solution

How to Undo the Effects of Man-Made Estrogen and Shrink Your Prostate
Scientists have discovered an amazing nutrient that can protect your prostate against BPA and estrogen. It’s called di-indolylmethane, or “DIM” for short. How does DIM protect your prostate? First, it reduces estrogen by converting it into “good” estrogen by-products. These estrogen by-products have been shown to enhance prostate health.5

Second, DIM lowers estrogen receptors in your prostate. By doing so, it blocks the activity of estrogen and its damaging effects on your prostate.6

Third, DIM also lowers the receptors in your prostate that take in DHT. High levels of these receptors can lead to prostate enlargement and increased PSA levels. By lowering these receptors, DIM helps promote normal prostate size and healthy PSA levels.7 In a clinical study, patients taking DIM saw a dramatic fall in their PSA.

But the benefits of DIM don’t end there. It also blocks oxidative stress and inflammation that can injure your prostate.8

Even more amazing, studies show DIM helps testosterone go up, you have more energy, more strength, and greater sex drive. That means, you can improve your sexual function and get back your manhood.

What’s more, research shows DIM can also help you lose weight and reduce your waistline. Plus, it boosts your immune system and helps you fight off viruses.

Experts have discovered strong evidence that there is a relationship between insulin-like growth factor and prostate cancer. This finding may make it possible for men to take steps to reduce their risk of developing prostate cancer by lowering their levels of this hormone if it is elevated.

What is insulin-like growth factor?
Insulin-like growth factor (IGF-1) is a hormone that helps promote normal tissue and bone growth and development. It has a structure that is similar to that of insulin, and it works in synch with growth hormone to reproduce and regenerate cells.

Previous investigations have revealed that having levels of IGF-1 that are too low or too high are risk markers for a wide variety of health challenges. For example, low IGF-1 has been associated with metabolic syndrome, obesity, chronic inflammatory diseases (e.g., rheumatoid arthritis, lupus), depression, and dementia, including Alzheimers disease.
High IGF-1, on the other hand, has been linked to acne and to a greater risk of developing and dying of cancer and cardiovascular disease, including heart disease and stroke.

Therefore, it appears it is important to strike a balance or normal level of IGF-1. The normal range for IGF-1 varies by gender and age and can be seen in this chart. You should discuss what is normal for you with your healthcare provider.

The relationship between insulin-like growth hormone and prostate cancer was examined by an international group of experts who conducted a meta-analysis that involved 19 studies and included 10,554 cases of prostate cancer and 13,618 controls. Data were collected on concentrations of five different IGFs. The reviewers reported that IGF-1 is highly likely to be involved in prostate cancer development.

Natural ways to lower IGF-1
For men who are interested in lowering their risk of prostate cancer, as well as other cancers and cardiovascular disease, there are several natural ways to reduce IGF-1 levels if they are elevated. For example:
Reduce protein intake. Numerous studies have shown that reducing protein intake will result in significantly lower IFG-1 levels. The secret, however, is that you need to reduce animal protein to reap this benefit. Thats because animal proteins, unlike those in plants, are rich in the amino acid methionine. Animal research has shown that when methionine intake is restricted, life span is lengthened. Therefore, it stands to reason that another way to lower IGF-1 levels would be to adopt the next suggestion:
Switch to plant protein. Plant protein contains a miniscule amount of methionine when compared with animal protein sources.
Get more glycine. The amino acid glycine helps lower IGF-1 by speeding up its clearance of methionine through the liver. You can take a glycine supplement like this one perhaps 2 to 3 grams dailyor you could consume plant proteins that have high levels of glycine, such as yeast and hemp protein powders (this is a highly rated one), and foods such as beans, cauliflower, cabbage, kale, and pumpkin.
Try intermittent fasting. Much of the evidence that intermittent fasting can lower IGF-1 is anecdotal, since few studies have been conducted. Restricting caloric intake for set time periods, such as eating normally for five days and then consuming just 600 or 700 calories for two days, reportedly lowers IGF-1 and other growth factors, which in turn allows the body to repair and heal itself.

Millions of men face prostate issues, with treatment with drugs and surgery often making their problems worse. A new study reveals that simply eating flaxseed may be the best way to improve your symptoms, and take back control of your health.

A study published in the Journal of Medicinal Food titled, “Efficacy and Safety of a Flaxseed Hull Extract in the Symptomatic Management of Benign Prostatic Hyperplasia: A Parallel, Randomized, Double-Blind, Placebo-Controlled, Pilot Study,” reveals that men who consumed an extract of flaxseed for swollen prostate (i.e. benign prostatic hyperplasia) saw significant improvement.

According to the study, The American Urology Association (AUA) Guideline, 2010, defines benign prostatic hyperplasia (BPH) as proliferation of smooth muscles and epithelial cells within the prostatic transition zone. The typical symptoms include:

Urinary frequency
Urgency
Nocturia (abnormal frequency of night time urination)
Decreased and intermittent force of stream
Sensation of incomplete bladder emptying.
BPH is one of the most widespread health conditions faced by men today, with the incidence rising to nearly 50% of the male population by the eighth decade of their lives. Moreover, countries like China and India are now seeing an exponential increase in BPH diagnoses as they increasingly adopt the Western diet, lifestyle, and medical system.

Current approaches include side effect heavy pharmaceuticals such as alpha adrenergic blockers and 5 a-reductase inhibitors, as well “gold standard” surgical procedures such as transurethral resection of the prostate (TURP), which so consistently produces surgery related impairments that there is an entire syndrome named after these side effects, namely, ​Transurethral Resection of the Prostate (TURP) Syndrome.

The human cost in both financial and existential terms is immense. This is why interest in safe, natural, affordable and effective alternatives is growing, and why the researchers felt compelled to test the hypothesis that eating flaxseed might provide an ideal alternative approach.

In the randomized, double-blinded, and placebo-controlled study, three groups of men, aged 45-75, with newly diagnosed BPH and an American Urological Association Symptom Index (AUASI) score of 13 , were given either a placebo, or a low or high dose of a lignin-rich flaxseed hull extract. More specifically:

“Study treatment consisted of 500 or 1000 mg of extract containing 100 mg (low-dose active [LDA] group, n = 26) or 200 mg (high-dose active [HDA] group, n = 26) of secoisolariciresinol diglucoside (SDG), respec- tively. The placebo (P) group (n = 28) received matching maltodextrin capsules. Sixty subjects (LDA [n = 19], HDA [n = 20], and P [n = 21]) completed the study as per the protocol requirements. Change in the AUASI score within a period of 8 weeks, from baseline to end of treatment, was assessed.”

The promising results were reported as follows:

“In this study, supplementation with the flaxseed hull extract provided greater relief than placebo in obstructive symptoms of BPH, such as sensation of incomplete bladder emptying, ”stopping and starting” while urinating, weak urinary stream, and ”straining while urinating.” Low and high doses of the flaxseed extract provided statistically significant improvements in the scores of these obstructive symptoms at week 8 as compared with baseline. In contrast to this, the placebo group did not show a statistically significant improvement with respect to these obstructive symptoms.”

The treatment group did not see any sign of increased side effects relative to the placebo group, indicating how remarkably safe flaxseed is versus conventional treatment. Also, because the placebo group also saw a significant improvement, it is possible that the strong placebo effect may have overshadowed the real power of the intervention. We hope that in the future a non-pharmaceutical industry funded study compares flaxseed to both pharmaceutical and surgical intervention to assess its true power.

Another important observation is that the flaxseed groups saw an increase in free testosterone, as well as a decrease in the testosterone metabolite DHT, which is known to contribute to prostate growth both benign and malignant. The placebo group, on the other hand, saw both an increase in testosterone and DHT. This also means that aging men, whose testosterone levels often plunge in relation to their estrogen levels, might experience additional hormonal benefits from eating flaxseed that could contribute to their overall state of well-being.

Concluding Remarks
This study is highly promising for a number of reasons. First, flaxseed is a safe, time-tested, and highly nutritious food that has been researched for a wide range of health benefits. You can view over 70 health benefits we have identified here: Flaxseed research database. Anything that can be used as a nourishing food while at the same time significantly relieving human suffering from a common disease, is highly compelling.

But there is a deeper reason why flaxseed may work so well. Our bodies co-evolved with certain foods for hundreds of thousands of years. Certain foods contains phytocompounds which our bodies have become dependent upon for self-regulation and homeostasis It is possible that lignins are vitally important, as essential as vitamins for maintaining optimal health. Obviously BPH is not caused by a lack of surgery or synthetic chemicals, but it might be true to say that BPH is caused by the lack of an ideal diet which would include lignin rich foods like flaxseed. Cleary, therefore, flaxseed could be considered part of a root cause resolution approach to BPH, versus looking it as just a palliative “disease management” tool like most of the approaches within the conventional armamentarium. We also recently reported on a study which found, in the first study of its kind, that sesame seed contains as high — if not a higher density — of lignans than flaxseed.

Finally, BPH falls within the category of a condition that involves the abnormal growth of the very same epithelial tissue that cancer emerges within. Since flaxseed has been found to prevent and even regress cancerous epithelial growths, such as breast cancer, it is highly likely that flaxseed consumption may also be the best insurance policy out there to prevent prostate cancer from developing.

5 Yoga Stretches to Relieve Symptoms of Prostate Enlargement
Kegels
Hero pose
Cobbler pose
Head-to-knee pose
Reclining big toe pose
Bow pose
Find a studio
Outlook
Overview
Exercising and strengthening the pelvic floor is one way to improve symptoms from an enlarged prostate, also known as benign prostatic hyperplasia (BPH). Benefits of strengthening the pelvic floor muscles include:

improved bladder and bowel control
improved recovery after prostate surgery
increased sexual satisfaction and orgasm potential
increased social confidence and quality of life
Yoga postures, or asanas, and Kegel exercises are low-impact ways to help strengthen the pelvic floor muscles. Performing the following yoga stretches can help you develop muscular control and flexibility in the pelvic region. The calming nature of these exercises may also help relieve stress and pelvic tension.

If you feel relaxed and comfortable, you may hold the poses for up to five minutes at a time. Hold more strenuous poses for up to 30 seconds. Remember, always modify or adjust the pose to suit your body as you go.

Kegel exercises
Kegel exercises are simple exercises you can do to strengthen your pelvic floor muscles. You can do these exercises on your own.

First, correctly identify your pelvic floor muscles. Theyre the group of muscles that support your bladder and regulate your urine flow. They include the bladder, sphincter muscles, and pelvic floor muscle.

To identify the pelvic floor muscles, imagine that youre trying to stop your urine flow while urinating. Do not do this while actually urinating. Squeeze, hold, and release the muscles a few times. Do the same with the sphincter muscles.

Now imagine that you are squeezing and lifting the pelvic floor muscles. You can do these exercises sitting, standing, on lying down on your back with your knees bent.

Make sure you have correctly identified the pelvic floor muscles and feel comfortable completing the exercises. Aim to do 3 sets of 12 squeezes per day. Hold each inward squeeze for up to 10 seconds and release. Relax for a few seconds between each repetition.

A 2013 study found that men who did pelvic floor exercises each day for 12 weeks following prostate surgery improved their urinary function and overall quality of life. They reduced lower urinary tract symptoms and had maximal urinary flow rate.

1. Hero (Virasana) pose

Sit between your feet with your knees down and your toes facing backward.
You may sit on a pillow for added support.
Keep your spine lengthened and rest your hands on your thighs, palms facing down.
Keep the weight in your hips and not your knees.
You can do your Kegel exercises while doing the pose.
To release the pose, roll over to one side and release your legs.

2. Cobbler pose (Baddha Konasana)

Sit down with your legs extended in front of you.
You may sit on the edge of a cushion for additional support in your hips.
Bend your knees to the side and place the soles of your feet together.
Pull your heels closer into your body to deepen the stretch, and move them farther away to lessen the stretch.
You may interlace your fingers and place them under the pinky toe sides of your feet.
After some time, walk your hands forward, round your spine, and tuck your chin to drop into a forward fold.
Breathe deeply and focus on relaxing and letting go of tension.
Release the pose by walking your hands back up and releasing your legs in front of you.
3. Head-to-knee pose (Janusirsasana)

Sit on the floor with both legs extended in front of you.
Bend your right knee and bring the sole of your right foot against your left inner thigh.
You may place a pillow under your sit bones or under your right knee for support.
Turn your torso to the left so your naval lines up with the inside of your left leg.
Place your hands on the floor beside you, or slowly walk them out in front of you.
Tuck your chin into your chest and hinge from the hips to come closer to the floor.
Its okay to round your spine and to bend the extended leg.
Slowly release on an inhale and walk your hands back as you lift your body.
Repeat on the opposite side.

4. Reclining big toe pose (Supta Padangusthasana)

Lie on your back with both legs extended and with a strap nearby.
Bend the left knee and pull your left thigh into your chest.
Press the right leg heavy into the floor while drawing your right toes back to your shin and pressing out through the sole of the right foot.
Put the strap around the arch of the left foot and hold the strap in both hands.
Straighten the left leg as you press the sole of the foot up toward the ceiling.
Walk your hands up the strap toward your foot, if possible, and press your shoulders into the floor while broadening across the collarbone.
If its comfortable, you can take hold of the strap with your left hand and allow your leg to fall out to the left side. Keep the right leg heavy and grounded to the floor.
To release, bring the leg back up to the top, release the strap, and hug the left leg back into your chest.
Repeat on the opposite leg.

5. Bow pose (Dhanurasana)

Lie down on your belly with your arms alongside the body, palms facing up.
Slowly bend your knees so your feet come up, and reach back with your hands to grasp the outside of your ankles.
Raise your head, chest, and shoulders off of the mat, if possible.
Try to keep your knees from splaying out to the side.
Look forward or up while taking long, deep breaths.
Hold for up to thirty seconds and release.
You may do this pose two times.
Finding a studio
You can practice yoga at home or, if youd like some extra guidance, you can go to a yoga studio. Its important to find a studio that suits your needs and makes you feel comfortable. Check out a few different studios in your area so you can decide which one is best for you.

Look for a studio that offers a variety of classes. Make sure the styles are suitable to your level and personal preference. You may want to choose a studio that focuses on the spiritual side of yoga as well as the physical.

Different styles may include:

Hatha
This is one of the most traditional styles of yoga. It focuses on breathing and classical yoga postures that are done slowly. The class is usually slow-paced and may focus on alignment. Meditation may also be included.

Yin
This is an excellent choice because it focuses on relaxing and letting go of tension, especially in the hips, pelvis, and lower spine. You work on lengthening connective tissues while in a meditative state. Poses are held for up to five minutes each.

Restorative
This type of yoga focuses on opening the body and relaxing the muscles. You use various props to hold poses for up to 20 minutes while entering a deep state of relaxation.

Kundalini
The aim of kundalini yoga is to bring up the energy stored at the base of your spine. It focuses on moving this energy up the spine and increasing physical vitality. Classes include meditation, mantra chanting, and physical postures.

Outlook
Yoga may help improve symptoms of an enlarged prostate without surgery or medications. Engaging in these exercises on a daily basis and eating a healthy diet may help improve your symptoms and your overall quality of life.

Learn more: 6 natural remedies for enlarged prostate (BPH)

Emily Cronkleton is a certified yoga teacher and has studied yoga in the United States, India, and Thailand. Her passion for yoga has laid the foundation for a healthy and inspired life. Her teachers and practice have helped shape her life experience in many ways.
https://www.youtube.com/watch?v=tq3X27c1bTc